In Camptothecins in Cancer Therapy, leading clinicians and researchers critically review our current understanding of camptothecins, their shortcomings, and the possibilities for improving their clinical performance.
eBook Title: Camptothecins in Cancer Therapy
Author:Thomas G. Burke (PhD.),Val R. Adams
Published on 2005-02 by Springer Science & Business Media
A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.
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Thomas G. Burke (PhD.),Val R. Adams
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- Camptothecins in Cancer Therapy published by Springer Science & Business Media since 2005-02 with ISBNs. The book ISBN 13 Code is 9781588290274 and ISBN 10 Code is 1588290271
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